BIEN 602 — Biomanufacturing for RNA Biologics

Fundamental and quantitative overview of RNA biologics. Introduction to RNA biologics associated biomanufacturing unit operations in upstream (design tools and large-scale production systems of DNA templates for in vitro RNA transcription; small-scale and large-scale RNA bioprocessing systems), and downstream approaches for RNA purification (like Tangential flow filtration and RNA-specific chromatography systems) for emerging mRNA therapeutics. Introduction to established and emerging applications of RNA biologics for gene and cell therapy.

• Credits: 3
• Faculty: Graduate Studies
• Department: Bioengineering
• Prerequisites: BIEN 590 or permission of the instructor